IPSCs Derived Cells

iPSCs-derived cells are specialized cell types generated through the directed differentiation of induced pluripotent stem cells (iPSCs). By mimicking embryonic development pathways, iPSCs can differentiate into virtually any cell type, including neurons, cardiomyocytes, hepatocytes, and immune cells. These cells are invaluable for applications in regenerative medicine, disease modeling, drug discovery, and personalized medicine.

Types of iPSCs-Derived Cells and Applications
  • Neurons:
    • Generation: Differentiation with neurotrophic factors like BDNF and NGF.
  • Cardiomyocytes:
    • Generation: Mesoderm induction followed by cardiogenic signaling (e.g., BMP4, Activin A).
  • Hepatocytes:
    • Generation: Endoderm differentiation using Activin A and hepatic growth factors.
Applications of iPSCs-Derived Cells
  • Disease Modeling:
    • Patient-derived iPSCs differentiate into diseased cell types for in vitro study of pathogenesis.
    • Example: Modeling genetic disorders like cystic fibrosis or sickle cell anemia.
  • Drug Discovery and Screening:
    • Test drug efficacy and toxicity on human-relevant cells.
    • Conduct high-throughput screens using iPSCs-derived cardiomyocytes or hepatocytes.
  • Regenerative Medicine:
    • Cell therapy development for degenerative diseases or injuries.
    • Examples: Retinal pigment epithelial (RPE) cells for macular degeneration, cardiomyocytes for myocardial infarction.

iPSCs-derived cells provide a transformative platform for understanding human biology and advancing therapeutic research. Their versatility, scalability, and relevance to human physiology make them indispensable tools in modern biomedical science.

AffiCELL® Human iPSC-Derived Photoreceptor Cells
CAT# AFG-CBG-1167
Size: 1 x 10^6
For Price Contact info@affigen.com 0.0 USD
AffiCELL® Human iPSC-Derived T Cells
CAT# AFG-CBG-1166
Size: 1 x 10^6
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
AffiCELL® Human iPSC-derived Hepatocytes
CAT# AFG-CBG-1164
Size: 1 x 10^6
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
AffiCELL® Human iPSC-derived Mesenchymal Stem Cells
CAT# AFG-CBG-1162
Size: 1 x 10^6
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
AffiCELL® Mouse iPSC-derived Endothelial Cells
CAT# AFG-CBG-1160
Size: 1 x 10^6
For Price Contact info@affigen.com 0.0 USD
AffiCELL® Human iPSC-derived Endothelial Cells
CAT# AFG-CBG-1159
Size: 1 x 10^6
For Price Contact info@affigen.com 0.0 USD
AffiCELL® Human iPSC-derived GABA neurons
CAT# AFG-CBG-1158
Size: 1 x 10^6
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
AffiCELL® Human iPSC-derived Cortical Neurons
CAT# AFG-CBG-1156
Size: 1 x 10^6
For Price Contact info@affigen.com 0.0 USD
AffiCELL® Human iPSC-derived Dopaminergic Neurons
CAT# AFG-CBG-1155
Size: 1 x 10^6
For Price Contact info@affigen.com 0.0 USD
AffiCELL® Human iPSC-derived Melanocytes
CAT# AFG-CBG-1154
Size: 1 x 10^6
For Price Contact info@affigen.com 0.0 USD
AffiCELL® Human iPSC-derived Keratinocytes
CAT# AFG-CBG-1153
Size: 1 x 10^6
For Price Contact info@affigen.com 0.0 USD
AffiCELL® Human iPSC-derived Osteoblasts
CAT# AFG-CBG-1152
Size: 1 x 10^6
For Price Contact info@affigen.com 0.0 USD
AffiCELL® Human iPSC-derived Schwann Cell
CAT# AFG-CBG-1151
Size: 1 x 10^6
For Price Contact info@affigen.com 0.0 USD
AffiCELL® Human iPSC-derived Sensory Neurons
CAT# AFG-CBG-1150
Size: 1 x 10^6
For Price Contact info@affigen.com 0.0 USD
AffiCELL® Human iPSC-derived Astrocytes
CAT# AFG-CBG-1149
Size: 1 x 10^6
For Price Contact info@affigen.com 0.0 USD
AffiCELL® Human iPSC-derived microglia
CAT# AFG-CBG-1148
Size: 1 x 10^6
For Price Contact info@affigen.com 0.0 USD
AffiCELL® Human iPSC-derived macrophages
CAT# AFG-CBG-1147
Size: 1 x 10^6
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD
AffiCELL® Human iPSC-Derived Motor Neurons
CAT# AFG-CBG-1144
Size: 1 x 10^6
For Price Contact info@affigen.com 0.0 USD
For Price Contact info@affigen.com 0.0 USD